A Rare Case of Paranasal Sinus Schwannoma with Intracranial Extension
Published: March 1, 2019 | DOI: https://doi.org/10.7860/JCDR/2019/35532.12731
Mihir Mohan Vaidya, Asha Sharad Shenoy, Naina Atul Goel
1. Fellow, Department of Neuropathology, Seth GSMC and KEM Hospital, Mumbai, Maharashtra, India.
2. Professor, Department of Pathology, Seth GSMC and KEM Hospital, Mumbai, Maharashtra, India.
3. Associate Professor, Department of Pathology, Seth GSMC and KEM Hospital, Mumbai, Maharashtra, India.
Correspondence
Dr. Asha Sharad Shenoy,
301, Arihant, 613-B,15th Road, Khar, Mumbai-400052, Maharashtra, India.
E-mail: shenoyasha@yahoo.co.in
Paranasal sinus schwannomas are uncommon and account for less than 4% of head and neck schwannomas. Intracranial extension and aggressive behaviour are very rarely observed in these tumours leading to misdiagnosis of a malignant neoplasm. Here, we report a case of a 35-year-old male with complaint of proptosis. MRI showed a tumour in the region of ethmoid sinus with expansion into anterior cranial fossa. Microscopy revealed a biphasic tumour with compact and loose areas. Tumour was composed of spindle cells with wavy nuclei, showing focal palisading and a strong immunoreactivity for S100. MIB-1 index was around 1%. A diagnosis of Schwannoma was favoured based on histology and immunohistochemistry.
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